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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APC
All Species:
13.33
Human Site:
S1837
Identified Species:
24.44
UniProt:
P25054
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P25054
NP_000029.2
2843
311646
S1837
N
E
D
R
V
R
G
S
F
A
F
D
S
P
H
Chimpanzee
Pan troglodytes
XP_001143509
2844
311637
S1837
N
E
D
R
V
R
G
S
F
A
F
D
S
P
H
Rhesus Macaque
Macaca mulatta
XP_001095216
2303
243755
G1312
E
R
G
G
G
T
G
G
A
G
L
H
F
A
G
Dog
Lupus familis
XP_536285
2273
247246
P1282
Y
T
P
I
E
G
T
P
Y
C
F
S
R
N
D
Cat
Felis silvestris
Mouse
Mus musculus
Q61315
2845
311071
T1835
N
E
D
R
V
R
G
T
F
A
L
D
S
P
H
Rat
Rattus norvegicus
P70478
2842
310514
G1835
N
E
D
R
V
R
G
G
F
T
F
D
S
P
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511806
2844
309621
S1842
N
E
D
R
V
R
G
S
Y
A
F
D
S
P
H
Chicken
Gallus gallus
XP_001233411
2232
244958
L1241
I
Q
Q
A
S
T
S
L
N
N
K
N
Q
P
E
Frog
Xenopus laevis
P70039
2829
310863
G1834
N
N
E
E
R
T
K
G
F
A
F
D
S
P
H
Zebra Danio
Brachydanio rerio
NP_001137312
2754
301074
A1751
P
Q
S
S
E
Y
R
A
R
M
L
K
R
P
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477152
2417
261266
A1426
T
K
E
P
G
A
R
A
Q
Q
M
Q
E
Q
P
Honey Bee
Apis mellifera
XP_624558
2760
306907
I1769
S
M
L
S
V
A
S
I
T
S
E
V
A
D
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783363
3212
346162
P2206
T
A
G
R
T
T
T
P
P
R
T
T
S
P
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
35
74.2
N.A.
90.4
90.1
N.A.
86.7
67.1
75
68
N.A.
23.8
22.8
N.A.
29.1
Protein Similarity:
100
99.5
49.4
76.1
N.A.
94.2
94.3
N.A.
92.7
72.2
84
78.2
N.A.
41
42
N.A.
45.1
P-Site Identity:
100
100
6.6
6.6
N.A.
86.6
86.6
N.A.
93.3
6.6
53.3
6.6
N.A.
0
6.6
N.A.
20
P-Site Similarity:
100
100
6.6
13.3
N.A.
93.3
86.6
N.A.
100
20
60
20
N.A.
20
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
0
16
0
16
8
39
0
0
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
39
0
0
0
0
0
0
0
0
47
0
8
8
% D
% Glu:
8
39
16
8
16
0
0
0
0
0
8
0
8
0
16
% E
% Phe:
0
0
0
0
0
0
0
0
39
0
47
0
8
0
0
% F
% Gly:
0
0
16
8
16
8
47
24
0
8
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
47
% H
% Ile:
8
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
8
0
0
0
8
8
0
0
0
% K
% Leu:
0
0
8
0
0
0
0
8
0
0
24
0
0
0
0
% L
% Met:
0
8
0
0
0
0
0
0
0
8
8
0
0
0
0
% M
% Asn:
47
8
0
0
0
0
0
0
8
8
0
8
0
8
0
% N
% Pro:
8
0
8
8
0
0
0
16
8
0
0
0
0
70
8
% P
% Gln:
0
16
8
0
0
0
0
0
8
8
0
8
8
8
0
% Q
% Arg:
0
8
0
47
8
39
16
0
8
8
0
0
16
0
8
% R
% Ser:
8
0
8
16
8
0
16
24
0
8
0
8
54
0
8
% S
% Thr:
16
8
0
0
8
31
16
8
8
8
8
8
0
0
0
% T
% Val:
0
0
0
0
47
0
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
8
0
0
16
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _